LDL MDA-treated (clone 10G10), anti-human
€905.00
In stock
SKU
250415
Protein Family: Transporters
Pathway and Disease: Metabolic Disorders
Description:
Low-density lipoprotein (LDL) is the carrier protein for cholesterol in the blood. LDL binds to its receptor on the capillary walls and thereby mediates the uptake and clearence of cholesterol from the circulation. In atherosclerotic lesions oxidatively modified LDL is found and oxidized LDL is specifically recognized and ingested by macrophages via scavenger receptor A and CD36. Oxidized LDL may be a marker of atherosclerosis but the precise changes in oxidized LDL are not well described. MDA-treated LDL appear to be different from LDL oxidized by other means. This antibody reacts with MDA-treated LDL but not with native LDL.
Alternate Names: low-density lipoprotein
Application Notes: Product Cat. No. 250415 reacts with MDA-treated LDL in ELISA and western blot. E: 1:16,000; WB: 1:1,000
Antigen: Low-density lipoprotein purified from human plasma and treated with malonyldialdehyde (MDA)
Format: Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Metabolic Disorders
Description:
Low-density lipoprotein (LDL) is the carrier protein for cholesterol in the blood. LDL binds to its receptor on the capillary walls and thereby mediates the uptake and clearence of cholesterol from the circulation. In atherosclerotic lesions oxidatively modified LDL is found and oxidized LDL is specifically recognized and ingested by macrophages via scavenger receptor A and CD36. Oxidized LDL may be a marker of atherosclerosis but the precise changes in oxidized LDL are not well described. MDA-treated LDL appear to be different from LDL oxidized by other means. This antibody reacts with MDA-treated LDL but not with native LDL.
Alternate Names: low-density lipoprotein
Application Notes: Product Cat. No. 250415 reacts with MDA-treated LDL in ELISA and western blot. E: 1:16,000; WB: 1:1,000
Antigen: Low-density lipoprotein purified from human plasma and treated with malonyldialdehyde (MDA)
Format: Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
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