LDLR polyclonal (Center), anti-human, mouse
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In stock
SKU
AC-AP8960C
Catalog Number: AC-AP8960C
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB22886
Applications: FC, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB22886
Applications: FC, WB
Datasheet
Request Information
Background:
The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place.
Other Names:
Low-density lipoprotein receptor, LDL receptor, LDLR
Target/Specificity:
This LDLR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 391-419 amino acids of human LDLR.
Antigen Region:
391-419
Antigen Type: Synthetic Peptide
Gene Name: LDLR
Gene ID: 3949
Primary Accession: P01130
NCBI Accession: NP_000518.1;NP_001182727.1;NP_001182728.1;NP_001182729.1;NP_001182732.1
Other Accession: P35952; P20063; Q28832; P35951; P35950; Q99088; Q99087; P01131
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place.
Other Names:
Low-density lipoprotein receptor, LDL receptor, LDLR
Target/Specificity:
This LDLR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 391-419 amino acids of human LDLR.
Antigen Region:
391-419
Antigen Type: Synthetic Peptide
Gene Name: LDLR
Gene ID: 3949
Primary Accession: P01130
NCBI Accession: NP_000518.1;NP_001182727.1;NP_001182728.1;NP_001182729.1;NP_001182732.1
Other Accession: P35952; P20063; Q28832; P35951; P35950; Q99088; Q99087; P01131
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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