LECT1 polyclonal (N-term), anti-human, mouse, rat
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In stock
SKU
AC-AP2729a
Catalog Number: AC-AP2729a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB15072
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB15072
Applications: WB
Datasheet
Request Information
Background:
LECT1 is a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it. The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1. The mature protein promotes chondrocyte growth and inhibits angiogenesis. This protein expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularization during development.
Other Names:
Leukocyte cell-derived chemotaxin 1, Chondrosurfactant protein, CH-SP, Chondromodulin-1, Chondromodulin-I, ChM-I, LECT1, CHMI
Target/Specificity:
This LECT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human LECT1.
Antigen Region:
1-30
Antigen Type: Synthetic Peptide
Gene Name: CNMD (HGNC:17005)
Gene ID: 11061
Primary Accession: O75829
NCBI Accession: NP_001011705.1;NP_008946.1
Other Accession: O77770; P17404
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
LECT1 is a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it. The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1. The mature protein promotes chondrocyte growth and inhibits angiogenesis. This protein expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularization during development.
Other Names:
Leukocyte cell-derived chemotaxin 1, Chondrosurfactant protein, CH-SP, Chondromodulin-1, Chondromodulin-I, ChM-I, LECT1, CHMI
Target/Specificity:
This LECT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human LECT1.
Antigen Region:
1-30
Antigen Type: Synthetic Peptide
Gene Name: CNMD (HGNC:17005)
Gene ID: 11061
Primary Accession: O75829
NCBI Accession: NP_001011705.1;NP_008946.1
Other Accession: O77770; P17404
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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