LEF-1 polyclonal, anti-human, mouse, rat

Protein Family: Transcription

Pathway and Disease: Signal Transduction, Endocrine System, Cell Communication, Cancers, Transcription

Description:
Lymphoid enhancer-binding factor 1 (LEF-1) participates in the Wnt signaling pathway. LEF-1 activates transcription of target genes in the presence of CTNNB1 and EP300. LEF-1 plays a role in hair cell differentiation and follicle morphogenesis, and regulates T-cell receptor alpha enhancer function.

Alternate Names: Lymphoid enhancer-binding factor 1, LEF-1, T cell-specific transcription factor 1-alpha, TCF1-alpha, LEF1

Application Notes: E: 1:10,000-1:50,,000; WB: 1:200-1:1,000

Accession No.: Q9UJU2

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human LEF-1.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.5 % BSA with 0.09% sodium azide. Antibody was purified by immunogen-affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.