LEF1 antibody (clone 2C9), anti-human
€435.00
In stock
SKU
AC-AT2693a
Catalog Number: AC-AT2693a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IF, E
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Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IF, E
Request Information AC-AT2693a">Request Information
Background:
This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.
Other Names:
Lymphoid enhancer-binding factor 1, LEF-1, T cell-specific transcription factor 1-alpha, TCF1-alpha, LEF1
Antigen Type:
Recombinant Protein
Gene Name: LEF1 (HGNC:6551)
Gene ID: 51176
NCBI Accession: NP_001124185.1;NP_001124186.1;NP_001159591.1;NP_057353.1
Primary Accession: Q9UJU2
Other Accession: NM_016269
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.
Other Names:
Lymphoid enhancer-binding factor 1, LEF-1, T cell-specific transcription factor 1-alpha, TCF1-alpha, LEF1
Antigen Type:
Recombinant Protein
Gene Name: LEF1 (HGNC:6551)
Gene ID: 51176
NCBI Accession: NP_001124185.1;NP_001124186.1;NP_001159591.1;NP_057353.1
Primary Accession: Q9UJU2
Other Accession: NM_016269
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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