LEF1 monoclonal (Ascites), anti-human

Background:
This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants

Other Names:
Lymphoid enhancer-binding factor 1, LEF-1, T cell-specific transcription factor 1-alpha, TCF1-alpha, LEF1

Target/Specificity:
This LEF1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 10-37 amino acids from human LEF1.

Antigen Region:
10-37

Antigen Type: Synthetic Peptide

Gene Name: LEF1 (HGNC:6551)
Gene ID: 51176
Primary Accession: Q9UJU2
NCBI Accession: NP_001124185.1;NP_001124186.1;NP_001159591.1;NP_057353.1
Other Accession: Q9QXN1; P27782; NP_057353.1
Format: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.