LEF1 polyclonal, anti-human, mouse, rat

Background:
This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.

Other Names:
Lymphoid enhancer-binding factor 1, LEF-1, T cell-specific transcription factor 1-alpha, TCF1-alpha, LEF1

Antigen Types:
Synthetic Peptide

Gene Name:
LEF1 (HGNC:6551)
Gene ID:
51176
Primary Accession: Q9UJU2
Other Accession: NP_057353;51176;16842 (mouse); 161452 (rat);