LEF1 polyclonal (N-term), anti-human
€0.00
In stock
SKU
AC-AP12048A
Catalog Number: AC-AP12048A
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB31989
Applications: IF, WB
Datasheet
Request Information
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB31989
Applications: IF, WB
Datasheet
Request Information
Background:
This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants
Other Names:
Lymphoid enhancer-binding factor 1, LEF-1, T cell-specific transcription factor 1-alpha, TCF1-alpha, LEF1
Target/Specificity:
This LEF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-37 amino acids from the N-terminal region of human LEF1.
Antigen Region:
10-37
Antigen Type: Synthetic Peptide
Gene Name: LEF1 (HGNC:6551)
Gene ID: 51176
Primary Accession: Q9UJU2
NCBI Accession: NP_001124185.1;NP_001124186.1;NP_001159591.1;NP_057353.1
Other Accession: Q9QXN1; P27782; NP_057353.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants
Other Names:
Lymphoid enhancer-binding factor 1, LEF-1, T cell-specific transcription factor 1-alpha, TCF1-alpha, LEF1
Target/Specificity:
This LEF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-37 amino acids from the N-terminal region of human LEF1.
Antigen Region:
10-37
Antigen Type: Synthetic Peptide
Gene Name: LEF1 (HGNC:6551)
Gene ID: 51176
Primary Accession: Q9UJU2
NCBI Accession: NP_001124185.1;NP_001124186.1;NP_001159591.1;NP_057353.1
Other Accession: Q9QXN1; P27782; NP_057353.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
|---|
Write Your Own Review