LEP antibody (clone M1), anti-human
€435.00
In stock
SKU
AC-AT2695a
Catalog Number: AC-AT2695a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: E
Request Information AC-AT2695a">Request Information
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: E
Request Information AC-AT2695a">Request Information
Background:
This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development.
Other Names:
Leptin, Obese protein, Obesity factor, LEP, OB, OBS
Antigen Type:
Recombinant Protein
Gene Name: LEP (HGNC:6553)
Gene ID: 3952
NCBI Accession: NP_000221.1
Primary Accession: P41159
Other Accession: BC060830
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development.
Other Names:
Leptin, Obese protein, Obesity factor, LEP, OB, OBS
Antigen Type:
Recombinant Protein
Gene Name: LEP (HGNC:6553)
Gene ID: 3952
NCBI Accession: NP_000221.1
Primary Accession: P41159
Other Accession: BC060830
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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