Lep Polyclonal Antibody

Background:
Leptin is a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. Leptin is the most critical hormone in the homeostatic regulation of energy balance among those so far discovered. Leptin primarily acts on the neurons of the mediobasal part of hypothalamus to regulate food intake, thermogenesis, and the blood glucose level. Leptin also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. Leptin has also been linked to type 2 diabetes mellitus development.

Research Area: Cancer, Cardiovascular, Metabolism, Neuroscience, Signaling transduction, Stem cells

Synonyms:
FLJ94114, LEP, LEP, LEPD, Leptin (murine obesity homolog), Leptin (obesity homolog, mouse), Leptin, Leptin Murine Obesity Homolog, Leptin Precursor Obesity Factor, OB, Obese protein, Obese, mouse, Obesity, Obesity factor, Obesity homolog, Obesity Murine Homolog Leptin, OBS, OTTHUMP00000212285

Immunogen: Recombinant Rat Leptin protein

Swissprot: P50596
Gene Accession: 25068

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 2 mg/mL
Dilution: IHC 1:50-1:100

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-48408,sc-9014,sc-843,sc-842