LEP polyclonal (N-term), anti-human
€0.00
In stock
SKU
AC-AP16666a
Catalog Number: AC-AP16666a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB36463
Applications: FC, IHC-P, WB, IF
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB36463
Applications: FC, IHC-P, WB, IF
Datasheet
Request Information
Background:
This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development. [provided by RefSeq].
Other Names:
Leptin, Obese protein, Obesity factor, LEP, OB, OBS
Target/Specificity:
This LEP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 8-37 amino acids from the N-terminal region of human LEP.
Antigen Region:
8-37
Antigen Type: Synthetic Peptide
Gene Name: LEP (HGNC:6553)
Gene ID: 3952
Primary Accession: P41159
NCBI Accession: NP_000221.1
Other Accession: P41160; NP_000221.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development. [provided by RefSeq].
Other Names:
Leptin, Obese protein, Obesity factor, LEP, OB, OBS
Target/Specificity:
This LEP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 8-37 amino acids from the N-terminal region of human LEP.
Antigen Region:
8-37
Antigen Type: Synthetic Peptide
Gene Name: LEP (HGNC:6553)
Gene ID: 3952
Primary Accession: P41159
NCBI Accession: NP_000221.1
Other Accession: P41160; NP_000221.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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