LEPREL1 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS71069
Background:
This gene encodes a member of the prolyl 3-hydroxylase subfamily of 2-oxo-glutarate-dependent dioxygenases. These enzymes play a critical role in collagen chain assembly, stability and cross-linking by catalyzing post-translational 3-hydroxylation of proline residues. Mutations in this gene are associated with nonsyndromic severe myopia with cataract and vitreoretinal degeneration, and downregulation of this gene may play a role in breast cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Alternative Name:
MCVD, MLAT4, LEPREL1,
Application Dilution: WB: 1:500 - 1:2000
Specificity: LEPREL1 polyclonal antibody detects endogenous levels of LEPREL1 protein.
Immunogen:
Recombinant Protein of human LEPREL1.
MW: ~ 81 kDa
Swis Prot.: Q8IVL5
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
This gene encodes a member of the prolyl 3-hydroxylase subfamily of 2-oxo-glutarate-dependent dioxygenases. These enzymes play a critical role in collagen chain assembly, stability and cross-linking by catalyzing post-translational 3-hydroxylation of proline residues. Mutations in this gene are associated with nonsyndromic severe myopia with cataract and vitreoretinal degeneration, and downregulation of this gene may play a role in breast cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Alternative Name:
MCVD, MLAT4, LEPREL1,
Application Dilution: WB: 1:500 - 1:2000
Specificity: LEPREL1 polyclonal antibody detects endogenous levels of LEPREL1 protein.
Immunogen:
Recombinant Protein of human LEPREL1.
MW: ~ 81 kDa
Swis Prot.: Q8IVL5
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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