LEPREL1 polyclonal, anti-human, mouse, rat

Background:
This gene encodes a member of the prolyl 3-hydroxylase subfamily of 2-oxo-glutarate-dependent dioxygenases. These enzymes play a critical role in collagen chain assembly, stability and cross-linking by catalyzing post-translational 3-hydroxylation of proline residues. Mutations in this gene are associated with nonsyndromic severe myopia with cataract and vitreoretinal degeneration, and downregulation of this gene may play a role in breast cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Synonyms: P3H2, LEPREL1, MCVD, MLAT4,

Cellular Location: Endoplasmic reticulum Golgi apparatus

Immunogen:
Recombinant Protein of human LEPREL1

Gene Symbol: LEPREL1

Gene ID: 55214

Swiss prot: Q8IVL5

Calculated MW: 81kDa

Recommended dilution:
WB 1:500-2000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.