LEPREL1 Polyclonal Antibody

Background:
This gene encodes a member of the prolyl 3-hydroxylase subfamily of 2-oxo-glutarate-dependent dioxygenases. These enzymes play a critical role in collagen chain assembly, stability and cross-linking by catalyzing post-translational 3-hydroxylation of proline residues. Mutations in this gene are associated with nonsyndromic severe myopia with cataract and vitreoretinal degeneration, and downregulation of this gene may play a role in breast cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Research Area: Neuroscience, Signal transduction

Synonyms:
P3H2, LEPREL1, MCVD, MLAT4

Immunogen: Recombinant fusion protein of human LEPREL1 (NP_060662.2).

Swissprot: Q8IVL5
Gene ID: 55214

Calculated MW: 60 kDa/80 kDa
Observed MW: 85 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.