Leptin (N-term) polyclonal, anti-human, mouse, rat

Protein Family: Cytokines

Pathway and Disease: Signal Transduction, Signaling Molecules and Interaction, Endocrine System

Description:
Leptin, the product of the ob (obese) gene, is a 16 kDa-protein consisting of 146 amino acid residues. Leptin is produced in the adipose tissue, and has an important role in appetite control, fat metabolism and regulation of body weight. Leptin targets the central nervous system, particularly hypothalamus, affecting food intake. Leptin levels are high in most obese individuals. Studies have shown that it may also influence reproductive function.

Alternate Names: Leptin, Obesity factor, Obese protein, LEP, OB, OBS

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:200-1:500

Accession No.: P41160

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of mouse Leptin.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 0.1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.