Leptin Receptor (LEPR) polyclonal (N-term), anti-human
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In stock
SKU
AC-AP6151a
Catalog Number: AC-AP6151a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB02053
Applications: IHC-P, WB, FC
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB02053
Applications: IHC-P, WB, FC
Datasheet
Request Information
Background:
Leptin, an adipocyte-specific hormone, regulates adipose-tissue mass through hypothalamic effects on satiety and energy expenditure by acting through the leptin receptor (LEPR). LEPR is a single-transmembrane-domain receptor of the cytokine receptor family that is identical to the mouse diabetes (db) gene product. During weight loss, leptin levels decrease, whereas soluble LEPR levels and the receptor bound fraction of leptin increases. The presence of LEPR in the absorptive cells of the small intestine suggests that leptin may have a physiological role in the regulation of nutrient absorption.
Other Names:
Leptin receptor, LEP-R, HuB219, OB receptor, OB-R, CD295, LEPR, DB, OBR
Target/Specificity:
This Leptin Receptor (LEPR) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-52 amino acids from the N-terminal region of human Leptin Receptor (LEPR).
Antigen Region:
23-52
Antigen Type: Synthetic Peptide
Gene Name: LEPR
Gene ID: 3953
Primary Accession: P48357
NCBI Accession: NP_001003679.1;NP_001003680.1;NP_001185616.1;NP_001185617.1;NP_001185618.1;NP_002294.2
Other Accession: NP_002294
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Leptin, an adipocyte-specific hormone, regulates adipose-tissue mass through hypothalamic effects on satiety and energy expenditure by acting through the leptin receptor (LEPR). LEPR is a single-transmembrane-domain receptor of the cytokine receptor family that is identical to the mouse diabetes (db) gene product. During weight loss, leptin levels decrease, whereas soluble LEPR levels and the receptor bound fraction of leptin increases. The presence of LEPR in the absorptive cells of the small intestine suggests that leptin may have a physiological role in the regulation of nutrient absorption.
Other Names:
Leptin receptor, LEP-R, HuB219, OB receptor, OB-R, CD295, LEPR, DB, OBR
Target/Specificity:
This Leptin Receptor (LEPR) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-52 amino acids from the N-terminal region of human Leptin Receptor (LEPR).
Antigen Region:
23-52
Antigen Type: Synthetic Peptide
Gene Name: LEPR
Gene ID: 3953
Primary Accession: P48357
NCBI Accession: NP_001003679.1;NP_001003680.1;NP_001185616.1;NP_001185617.1;NP_001185618.1;NP_002294.2
Other Accession: NP_002294
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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