Leptin Receptor polyclonal, anti-human, mouse, rat

Background:
Receptor for obesity factor (leptin). On ligand binding, mediates signaling through JAK2/STAT3. Involved in the regulation of fat metabolism and, in a hematopoietic pathway, required for normal lymphopoiesis. May play a role in reproduction. Can also mediate the ERK/FOS signaling pathway.

Alternative Name:
LEP-R, OB-R, LEPR, DB, OBR, CD 295, CD295, CD295 antigen, Db, Fa, HuB219, LEP R, LEP-R, LEPR, LEPR, LEPRD, Leptin receptor, Leptin receptor fatty, Leptin receptor gene related protein, Leptin receptor precursor, Leptin receptor precursor, OB R gene related protein, OB receptor, OB-R, OB-RGRP, obl, Obr,

Application Dilution:
FC:1:50-1:100
WB:1:500-1:1,000

Specificity: Leptin Receptor polyclonal antibody detects endogenous levels of Leptin Receptor protein.

Immunogen:
recombinant protein

MW: 132 kDa

Swiss-Prot: P48357(Human) P48356(Mouse) Q62959(Rat)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.