LETMD1 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS6793
Background:
HCCR-1 (human cervical cancer oncogene 1), also known as HCCR-2 or LETMD1, is a 360 amino acid single-pass membrane protein that is expressed in the kidney, liver, skeletal muscle, heart and brain. It is suggested that HCCR-1 may be involved in tumorigenesis and may function as a negative regulator of the p53 tumor suppressor. Overexpression of HCCR-1 may cause mitochondrial dysfunction that can lead to UVC or staurosporine-induced apoptosis resistance and progression of tumor formation.
Alternative Name:
HCCR1, HCCR-1, HCCR-2, HCRR-2, 1110019O13Rik,
Application Dilution: WB: 1:500~1:2000, IHC/IF: 1:50~1:200
Specificity: LETMD1 polyclonal antibody detects endogenous levels of LETMD1 protein.
Immunogen:
Recombinant full length Human LETMD1.
MW: ~ 42 kDa
Swis Prot.: Q6P1Q0
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
HCCR-1 (human cervical cancer oncogene 1), also known as HCCR-2 or LETMD1, is a 360 amino acid single-pass membrane protein that is expressed in the kidney, liver, skeletal muscle, heart and brain. It is suggested that HCCR-1 may be involved in tumorigenesis and may function as a negative regulator of the p53 tumor suppressor. Overexpression of HCCR-1 may cause mitochondrial dysfunction that can lead to UVC or staurosporine-induced apoptosis resistance and progression of tumor formation.
Alternative Name:
HCCR1, HCCR-1, HCCR-2, HCRR-2, 1110019O13Rik,
Application Dilution: WB: 1:500~1:2000, IHC/IF: 1:50~1:200
Specificity: LETMD1 polyclonal antibody detects endogenous levels of LETMD1 protein.
Immunogen:
Recombinant full length Human LETMD1.
MW: ~ 42 kDa
Swis Prot.: Q6P1Q0
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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