LGALS3 polyclonal, anti-human, mouse, rat

Background:
This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.

Synonyms: CBP35, GAL3, GALBP, GALIG, L31, LGALS2, MAC2

Cellular Location: Cytoplasm Nucleus Secreted

Immunogen:
Recombinant protein of human LGALS3

Gene Symbol: LGALS3

Gene ID: 3958

Swiss prot: P17931

Calculated MW: 26kDa

Recommended dilution:
IHC 1:50-200, IHC 1:50-200, IF 1:20-50

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.