LGALS3 Polyclonal Antibody

Background:
This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.

Research Area: Cell Biology, Epigenetics and Nuclear Signaling, Stem Cells, Cancer

Synonyms:
LGALS3, CBP35, GAL3, GALBP, GALIG, L31, LGALS2, MAC2

Immunogen: Recombinant fusion protein of human LGALS3 (NP_002297.2).

Swissprot: P17931
Gene ID: 3958

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "IHC 1:50-1:200 IF 1:20-1:50"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.