LGALS3BP polyclonal (Center), anti-human, mouse
€0.00
In stock
SKU
AC-AP19780c
Catalog Number: AC-AP19780c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB40516
Applications: IHC-P-Leica, WB
Datasheet
Request Information
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB40516
Applications: IHC-P-Leica, WB
Datasheet
Request Information
Background:
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1.
Other Names:
Galectin-3-binding protein, Basement membrane autoantigen p105, Lectin galactoside-binding soluble 3-binding protein, Mac-2-binding protein, MAC2BP, Mac-2 BP, Tumor-associated antigen 90K, LGALS3BP, M2BP
Target/Specificity:
This LGALS3BP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 383-412 amino acids from the Central region of human LGALS3BP.
Antigen Region:
383-412
Antigen Type: Synthetic Peptide
Gene Name: LGALS3BP
Gene ID: 3959
Primary Accession: Q08380
NCBI Accession: NP_005558.1
Other Accession: NP_005558.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1.
Other Names:
Galectin-3-binding protein, Basement membrane autoantigen p105, Lectin galactoside-binding soluble 3-binding protein, Mac-2-binding protein, MAC2BP, Mac-2 BP, Tumor-associated antigen 90K, LGALS3BP, M2BP
Target/Specificity:
This LGALS3BP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 383-412 amino acids from the Central region of human LGALS3BP.
Antigen Region:
383-412
Antigen Type: Synthetic Peptide
Gene Name: LGALS3BP
Gene ID: 3959
Primary Accession: Q08380
NCBI Accession: NP_005558.1
Other Accession: NP_005558.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
|---|
Write Your Own Review