LGI1 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS71949
Background:
This gene encodes a member of the secreted leucine-rich repeat (LRR) superfamily and shares homology with members of the SLIT protein family. The encoded protein may regulate the activity of voltage-gated potassium channels and may be involved in neuronal growth regulation and cell survival. This gene is rearranged as a result of translocations in glioblastoma cell lines, and it is frequently down-regulated or rearranged in malignant gliomas. Mutations in this gene result in autosomal dominant lateral temporal epilepsy. Alternative splicing results in multiple transcript variants.
Alternative Name:
ADLTE, ADPAEF, ADPEAF, EPITEMPIN, EPT, ETL1, IB1099
Application Dilution: WB: 1:500 - 1:2000
Specificity: LGI1 polyclonal antibody detects endogenous levels of LGI1 protein.
Immunogen:
Recombinant protein of human LGI1
MW: 64kDa
Swis Prot.: O95970
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
This gene encodes a member of the secreted leucine-rich repeat (LRR) superfamily and shares homology with members of the SLIT protein family. The encoded protein may regulate the activity of voltage-gated potassium channels and may be involved in neuronal growth regulation and cell survival. This gene is rearranged as a result of translocations in glioblastoma cell lines, and it is frequently down-regulated or rearranged in malignant gliomas. Mutations in this gene result in autosomal dominant lateral temporal epilepsy. Alternative splicing results in multiple transcript variants.
Alternative Name:
ADLTE, ADPAEF, ADPEAF, EPITEMPIN, EPT, ETL1, IB1099
Application Dilution: WB: 1:500 - 1:2000
Specificity: LGI1 polyclonal antibody detects endogenous levels of LGI1 protein.
Immunogen:
Recombinant protein of human LGI1
MW: 64kDa
Swis Prot.: O95970
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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