LGR5 polyclonal, anti-human, mouse, rat

Background:
The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene.

Synonyms: FEX, GPR49, GPR67, GRP49, HG38

Cellular Location: Cell membrane Golgi apparatus Multi-pass membrane protein trans-Golgi network membrane

Immunogen:
Recombinant protein of human LGR5

Gene Symbol: LGR5

Gene ID: 8549

Swiss prot: O75473

Calculated MW: 100kDa

Recommended dilution:
WB 1:1000-2000, IHC 1:50-200, IF 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.