LGR5 Polyclonal Antibody

Background:
The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene.

Research Area: Cancer, Signal Transduction, Stem Cells

Synonyms:
LGR5, FEX, GPR49, GPR67, GRP49, HG38

Immunogen: Recombinant fusion protein of human LGR5 (NP_003658.1).

Swissprot: O75473
Gene ID: 8549

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: IF 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.