LIG3 Polyclonal Antibody

Background:
This gene is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. The protein encoded by this gene is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
LIG3, LIG2

Immunogen: Recombinant fusion protein of human LIG3 (NP_039269.2).

Swissprot: P49916
Gene ID: 3980

Calculated MW: 95 kDa/102 kDa/106 kDa/112 kDa
Observed MW: 112 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.