LILRA3 antibody (clone 2000000000), anti-human
€435.00
In stock
SKU
AC-AT2714a
Catalog Number: AC-AT2714a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB
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Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB
Request Information AC-AT2714a">Request Information
Background:
Leukocyte Ig-like receptors (LIRs) are a family of immunoreceptors expressed predominantly on monocytes and B cells and at lower levels on dendritic cells and natural killer (NK) cells. All LIRs in subfamily B have an inhibitory function (see, e.g., LILRB1, MIM 604811). LIRs in subfamily A, with short cytoplasmic domains lacking an immunoreceptor tyrosine-based inhibitory motif (ITIM) and with transmembrane regions containing a charged arginine residue, may initiate stimulatory cascades (see LILRA1, MIM 604810). One member of subfamily A (LILRA3) lacks a transmembrane region and is presumed to be a soluble receptor (Borges et al., 1997 [PubMed 9548455]).
Other Names:
Leukocyte immunoglobulin-like receptor subfamily A member 3, CD85 antigen-like family member E, Immunoglobulin-like transcript 6, ILT-6, Leukocyte immunoglobulin-like receptor 4, LIR-4, Monocyte inhibitory receptor HM43/HM31, CD85e, LILRA3, ILT6, LIR4
Antigen Type:
Recombinant Protein
Gene Name: LILRA3
Gene ID: 11026
NCBI Accession: NP_001166125.1;NP_006856.3
Primary Accession: Q8N6C8
Other Accession: BC028208
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Leukocyte Ig-like receptors (LIRs) are a family of immunoreceptors expressed predominantly on monocytes and B cells and at lower levels on dendritic cells and natural killer (NK) cells. All LIRs in subfamily B have an inhibitory function (see, e.g., LILRB1, MIM 604811). LIRs in subfamily A, with short cytoplasmic domains lacking an immunoreceptor tyrosine-based inhibitory motif (ITIM) and with transmembrane regions containing a charged arginine residue, may initiate stimulatory cascades (see LILRA1, MIM 604810). One member of subfamily A (LILRA3) lacks a transmembrane region and is presumed to be a soluble receptor (Borges et al., 1997 [PubMed 9548455]).
Other Names:
Leukocyte immunoglobulin-like receptor subfamily A member 3, CD85 antigen-like family member E, Immunoglobulin-like transcript 6, ILT-6, Leukocyte immunoglobulin-like receptor 4, LIR-4, Monocyte inhibitory receptor HM43/HM31, CD85e, LILRA3, ILT6, LIR4
Antigen Type:
Recombinant Protein
Gene Name: LILRA3
Gene ID: 11026
NCBI Accession: NP_001166125.1;NP_006856.3
Primary Accession: Q8N6C8
Other Accession: BC028208
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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