LILRB2 polyclonal, anti-human, mouse, rat

Background:
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms: CD85D, ILT-4, ILT4, LIR-2, LIR2, MIR-10, MIR10

Cellular Location: Membrane Single-pass type I membrane protein

Immunogen:
Recombinant protein of human LILRB2

Gene Symbol: LILRB2

Gene ID: 10288

Swiss prot: Q8N423

Calculated MW: 65kDa

Recommended dilution:
WB 1:1000-4000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.