LILRB4 Antibody (N-term) Blocking peptide
€363.00
In stock
SKU
AC-BP12297a
Background:
This gene is a member of the leukocyte immunoglobulin-likereceptor (LIR) family, which is found in a gene cluster atchromosomal region 19q13.4. The encoded protein belongs to thesubfamily B class of LIR receptors which contain two or fourextracellular immunoglobulin domains, a transmembrane domain, andtwo to four cytoplasmic immunoreceptor tyrosine-based inhibitorymotifs (ITIMs). The receptor is expressed on immune cells where itbinds to MHC class I molecules on antigen-presenting cells andtransduces a negative signal that inhibits stimulation of an immuneresponse. The receptor can also function in antigen capture andpresentation. It is thought to control inflammatory responses andcytotoxicity to help focus the immune response and limitautoreactivity. Multiple transcript variants encoding differentisoforms have been found for this gene.
Other Names:
Leukocyte immunoglobulin-like receptor subfamily B member 4, CD85 antigen-like family member K, Immunoglobulin-like transcript 3, ILT-3, Leukocyte immunoglobulin-like receptor 5, LIR-5, Monocyte inhibitory receptor HM18, CD85k, LILRB4, ILT3, LIR5
Gene Name: LILRB4
Gene ID: 11006
Primary Accession: Q8NHJ6
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene is a member of the leukocyte immunoglobulin-likereceptor (LIR) family, which is found in a gene cluster atchromosomal region 19q13.4. The encoded protein belongs to thesubfamily B class of LIR receptors which contain two or fourextracellular immunoglobulin domains, a transmembrane domain, andtwo to four cytoplasmic immunoreceptor tyrosine-based inhibitorymotifs (ITIMs). The receptor is expressed on immune cells where itbinds to MHC class I molecules on antigen-presenting cells andtransduces a negative signal that inhibits stimulation of an immuneresponse. The receptor can also function in antigen capture andpresentation. It is thought to control inflammatory responses andcytotoxicity to help focus the immune response and limitautoreactivity. Multiple transcript variants encoding differentisoforms have been found for this gene.
Other Names:
Leukocyte immunoglobulin-like receptor subfamily B member 4, CD85 antigen-like family member K, Immunoglobulin-like transcript 3, ILT-3, Leukocyte immunoglobulin-like receptor 5, LIR-5, Monocyte inhibitory receptor HM18, CD85k, LILRB4, ILT3, LIR5
Gene Name: LILRB4
Gene ID: 11006
Primary Accession: Q8NHJ6
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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