LILRB5 Polyclonal Antibody

Background:
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response. Multiple transcript variants encoding different isoforms have been found for this gene.

Research Area: Immunology

Synonyms:
CD85 antigen-like family member C, CD85c, Leukocyte immunoglobulin-like receptor 8, Leukocyte immunoglobulin-like receptor subfamily B member 5, LILRB5, LIR-8, LIR8, LIRB5

Immunogen: Synthetic peptide of human LILRB5

Swissprot: O75023
Gene Accession: NP006831

Calculated MW: 64 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.72 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:10-1:50, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.