LIMK1 polyclonal, anti-human, mouse, rat antibody
€295.00
In stock
SKU
AC-ABV10315-100
Catalog Number: AC-ABV10315-100
Size: 100 µg
Host: Rabbit IgG
Applications: WB, IP
Datasheet
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Size: 100 µg
Host: Rabbit IgG
Applications: WB, IP
Datasheet
Request Information
Background:
LIM kinases (LIMK1 and LIMK2) are serine/threnine kinases that have two zinc finger motifs, known as LIM motifs in their N-terminal regulatory domain. LIM kinases are involved in actin cytoskeleton regulation thro µgh Rho-family GTPases and downstream kinases PAKs and ROCK. PAK1 and ROCK phosphorylate LIMK1 and LIMK2, which increases the activity of the kinases. Activated LIM kinases inhibit the actin depolymerization activity of cofilin by phosphorylation at the N-terminus of Cofilin.
Other Names:
LIM kinases, LIMK-1
Primary Accession: P53667
Gene Name: LIMK1
Gene ID: 3984
Concentration (mg/ml): 0.5 mg/ml
LIM kinases (LIMK1 and LIMK2) are serine/threnine kinases that have two zinc finger motifs, known as LIM motifs in their N-terminal regulatory domain. LIM kinases are involved in actin cytoskeleton regulation thro µgh Rho-family GTPases and downstream kinases PAKs and ROCK. PAK1 and ROCK phosphorylate LIMK1 and LIMK2, which increases the activity of the kinases. Activated LIM kinases inhibit the actin depolymerization activity of cofilin by phosphorylation at the N-terminus of Cofilin.
Other Names:
LIM kinases, LIMK-1
Primary Accession: P53667
Gene Name: LIMK1
Gene ID: 3984
Concentration (mg/ml): 0.5 mg/ml
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