LIN28A polyclonal (C-term), anti-human
€0.00
In stock
SKU
AC-AP2765b
Catalog Number: AC-AP2765b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB14266
Applications: IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB14266
Applications: IHC-P, WB
Datasheet
Request Information
Background:
LIN28A acts as a 'translational enhancer', driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. Its association with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in stabilizing the mRNAs. It binds IGF2 mRNA, MYOD1 mRNA, ARBP/36B4 ribosomal protein mRNA and its own mRNA. It is essential for skeletal muscle differentiation through the translational up-regulation of IGF2 expression.
Other Names:
Protein lin-28 homolog A, Lin-28A, Zinc finger CCHC domain-containing protein 1, LIN28A, CSDD1, LIN28, ZCCHC1
Target/Specificity:
This LIN28A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168~198 amino acids from the C-terminal region of human LIN28A.
Antigen Region:
168-198
Antigen Type: Synthetic Peptide
Gene Name: LIN28A
Gene ID: 79727
Primary Accession: Q9H9Z2
NCBI Accession: NP_078950.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
LIN28A acts as a 'translational enhancer', driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. Its association with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in stabilizing the mRNAs. It binds IGF2 mRNA, MYOD1 mRNA, ARBP/36B4 ribosomal protein mRNA and its own mRNA. It is essential for skeletal muscle differentiation through the translational up-regulation of IGF2 expression.
Other Names:
Protein lin-28 homolog A, Lin-28A, Zinc finger CCHC domain-containing protein 1, LIN28A, CSDD1, LIN28, ZCCHC1
Target/Specificity:
This LIN28A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168~198 amino acids from the C-terminal region of human LIN28A.
Antigen Region:
168-198
Antigen Type: Synthetic Peptide
Gene Name: LIN28A
Gene ID: 79727
Primary Accession: Q9H9Z2
NCBI Accession: NP_078950.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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