LIN7B polyclonal (N-term), anti-human, mouse
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In stock
SKU
AC-AP19782a
Catalog Number: AC-AP19782a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB40557
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB40557
Applications: WB
Datasheet
Request Information
Background:
Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells. May increase the amplitude of ACCN3 acid-evoked currents by stabilizing the channel at the cell surface (By similarity).
Other Names:
Protein lin-7 homolog B, Lin-7B, hLin7B, Mammalian lin-seven protein 2, MALS-2, Vertebrate lin-7 homolog 2, Veli-2, hVeli2, LIN7B, MALS2, VELI2
Target/Specificity:
This LIN7B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 35-62 amino acids from the N-terminal region of human LIN7B.
Antigen Region:
35-62
Antigen Type: Synthetic Peptide
Gene Name: LIN7B
Gene ID: 64130
Primary Accession: Q9HAP6
NCBI Accession: NP_071448.1
Other Accession: Q9Z252; O88951; Q2KIB6; NP_071448.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells. May increase the amplitude of ACCN3 acid-evoked currents by stabilizing the channel at the cell surface (By similarity).
Other Names:
Protein lin-7 homolog B, Lin-7B, hLin7B, Mammalian lin-seven protein 2, MALS-2, Vertebrate lin-7 homolog 2, Veli-2, hVeli2, LIN7B, MALS2, VELI2
Target/Specificity:
This LIN7B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 35-62 amino acids from the N-terminal region of human LIN7B.
Antigen Region:
35-62
Antigen Type: Synthetic Peptide
Gene Name: LIN7B
Gene ID: 64130
Primary Accession: Q9HAP6
NCBI Accession: NP_071448.1
Other Accession: Q9Z252; O88951; Q2KIB6; NP_071448.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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