Lipoprotein lipase polyclonal, anti-human

Background:
The Lipase gene family belongs to one of the most robust genetic superfamilies found in living organisms, which includes esterases and thioesterases. Lipase gene products are related by tertiary structure rather than primary amino acid sequence. Members of the AB hydrolase subfamily include hepatic lipase (HL), endothelial lipase (EL), lipoprotein lipase (LPL) and pancreatic lipase (PL). HL balances the composition and transport of lipoproteins in human plasma. Synthesized in endothelial cells, EL hydrolyzes high density lipoproteins. LPL, a homodimer attached to the membrane by a GPI-anchor, mediates the hydrolysis of triglycerides of very low density lipoproteins and circulating chylomicrons. Defects in LPL may cause chylomicronemia syndrome or a form of lipoprotein lipase deficiency characterized by hypertriglyceridemia.

Alternative Name:
LPL, LIPD, EC 3.1.1, EC 3.1.1.34, HDLCQ11, LIPD, LIPL, Lipoprotein lipase, LPL, LPL protein, MGC137861,

Application Dilution:
WB:1:500-1:1,000
IHC:1:50-1:200

Specificity: Lipoprotein lipase polyclonal antibody detects endogenous levels of Lipoprotein lipase protein.

Immunogen:
recombinant protein

MW: 53 kDa

Swiss-Prot: P06858(Human)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.