LIS1 / PAFAH1B1 polyclonal, anti-human, rat

Background:
This locus was identified as encoding a gene that when mutated or lost caused the lissencephaly associated with Miller-Dieker lissencephaly syndrome. This gene encodes the non-catalytic alpha subunit of the intracellular Ib isoform of platelet-activating factor acteylhydrolase, a heterotrimeric enzyme that specifically catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist: one composed of multiple subunits, the other, a single subunit. In addition, a single-subunit isoform of this enzyme is found in serum.

Other Names:
Platelet-activating factor acetylhydrolase IB subunit alpha {ECO:0000255|HAMAP-Rule:MF_03141}, Lissencephaly-1 protein {ECO:0000255|HAMAP-Rule:MF_03141}, LIS-1 {ECO:0000255|HAMAP-Rule:MF_03141}, PAF acetylhydrolase 45 kDa subunit {ECO:0000255|HAMAP-Rule:MF_03141}, PAF-AH 45 kDa subunit {ECO:0000255|HAMAP-Rule:MF_03141}, PAF-AH alpha {ECO:0000255|HAMAP-Rule:MF_03141}, PAFAH alpha {ECO:0000255|HAMAP-Rule:MF_03141}, PAFAH1B1 {ECO:0000255|HAMAP-Rule:MF_03141}

Antigen Types:
Synthetic Peptide

Gene Name:
LIS1
Gene ID:
5048
Primary Accession: P43034
Other Accession: NP_000421;5048;