LKB1 polyclonal, anti-human

Quantity: 100 µg

Background:
Serine/threonine kinase 11 or LKB1 is a protein kinase which in humans is encoded by the STK11 gene. The STK11 gene, which encodes a member of the serine/threonine kinase, regulates cell polarity and functions as a tumour suppressor. STK11 is a primary upstream kinase of adenine monophosphate-activated protein kinase (AMPK), a necessary element in cell metabolism that is required for maintaining energy homeostasis. It has been found that LKB1 physically associates with p53 and regulates specific p53-dependent apoptosis pathways. The STK11 gene extends over 23 kb of genomic DNA and is composed of 9 exons, which are transcribed in telomere-to-centromere direction.

Description:
Rabbit IgG polyclonal antibody for Serine/threonine-protein kinase STK11 (STK11) detection. Tested with WB in Human.

Synonyms:
hLKB1 antibody, Liver kinase B1 antibody, LKB 1 antibody, LKB1 antibody, NY REN 19 antigen antibody, Peutz Jeghers syndrome antibody, PJS antibody, Polarization related protein LKB1 antibody, Renal carcinoma antigen NY-REN-19 antibody, Serine/Threonine Kinase 11 antibody, Serine/threonine protein kinase 11 antibody, Serine/threonine protein kinase LKB1 antibody, Serine/threonine protein kinase STK11 antibody, Serine/threonine-protein kinase 11 antibody, Serine/threonine-protein kinase LKB1 antibody, Serine/threonine-protein kinase XEEK1 antibody, STK 11 antibody, STK11 antibody, STK11_HUMAN antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human LKB1 recombinant protein (Position: K62-C430). Human LKB1 shares 89% amino acid (aa) sequence identity with both mouse and rat LKB1.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.