LKB1 polyclonal, anti-human, mouse, rat

Background:
This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

Synonyms: STK11,PJS,hLKB1,serine/threonine kinase 11

Cellular Location: Cytoplasm

Immunogen:
A synthetic peptide of human LKB1

Gene Symbol: LKB1

Gene ID: 6794

Swiss prot: Q15831

Calculated MW: 49/45kDa

Recommended dilution:
IHC 1:50-200

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.