LKB1 Polyclonal Antibody

Background:
This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

Research Area: Cancer, Cell Biology, Metabolism

Synonyms:
LKB1, PJS, hLKB1, STK11

Immunogen: Recombinant fusion protein of human LKB1 (NP_000446.1).

Swissprot: Q15831
Gene ID: 6794

Calculated MW: 45 kDa/48 kDa
Observed MW: 54 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.