LLGL1/2 polyclonal (Center S645/S649), anti-human
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In stock
SKU
AC-AP14311c
Catalog Number: AC-AP14311c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB07627
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB07627
Applications: WB
Datasheet
Request Information
Background:
The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. This human gene encodes a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells. Alternative splicing results in multiple transcript variants encoding different isoforms.
Other Names:
Lethal(2) giant larvae protein homolog 2, HGL, LLGL2
Target/Specificity:
This LLGL1/2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 624-653 amino acids from the Central region of human LLGL1/2.
Antigen Region:
624-653
Antigen Type: Synthetic Peptide
Gene Name: LLGL2
Gene ID: 3993
Primary Accession: Q6P1M3
NCBI Accession: NP_001015002.1;NP_001026973.1;NP_004515.2
Other Accession: Q3TJ91; Q8K4K5; Q80Y17; Q15334; Q8MKF0; NP_004515.2; NP_001015002.1; NP_001026973.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. This human gene encodes a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells. Alternative splicing results in multiple transcript variants encoding different isoforms.
Other Names:
Lethal(2) giant larvae protein homolog 2, HGL, LLGL2
Target/Specificity:
This LLGL1/2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 624-653 amino acids from the Central region of human LLGL1/2.
Antigen Region:
624-653
Antigen Type: Synthetic Peptide
Gene Name: LLGL2
Gene ID: 3993
Primary Accession: Q6P1M3
NCBI Accession: NP_001015002.1;NP_001026973.1;NP_004515.2
Other Accession: Q3TJ91; Q8K4K5; Q80Y17; Q15334; Q8MKF0; NP_004515.2; NP_001015002.1; NP_001026973.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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