LLGL2 Antibody (N-term) Blocking Peptide

Background:
The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. LLGL2 is a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells.

Other Names:
Lethal(2) giant larvae protein homolog 2, HGL, LLGL2

Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP2199b was selected from the N-term region of human LLGL2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Gene Name: LLGL2

Gene ID: 3993
Primary Accession: Q6P1M3
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.