LMAN1 polyclonal, anti-human, mouse, rat

Background:
The protein encoded by this gene is a membrane mannose-specific lectin that cycles between the endoplasmic reticulum, endoplasmic reticulum-Golgi intermediate compartment, and cis-Golgi, functioning as a cargo receptor for glycoprotein transport. The protein has an N-terminal signal sequence, a calcium-dependent and pH-sensitive carbohydrate recognition domain, a stalk region that functions in oligomerization, a transmembrane domain, and a short cytoplasmic domain required for organelle targeting. Allelic variants of this gene are associated with the autosomal recessive disorder combined factor V-factor VIII deficiency.

Synonyms: ERGIC-53, ERGIC53, F5F8D, FMFD1, MCFD1, MR60, gp58

Cellular Location: Endoplasmic reticulum membrane Endoplasmic reticulum-Golgi intermediate compartment membrane Golgi apparatus membrane Single-pass membrane protein Single-pass type I membrane protein

Immunogen:
Recombinant protein of human LMAN1

Gene Symbol: LMAN1

Gene ID: 3998

Swiss prot: P49257

Calculated MW: 58kDa

Recommended dilution:
WB 1:500-2000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.