LMNA monoclonal, anti-human, mouse, rat
€0.00
In stock
SKU
AC-AM8634b
Catalog Number: AC-AM8634b
Size: 50 µl, 200 µl
Isotype: mouse IgG1,k
Clone Name: 1073CT3.1.3
Applications: WB
Datasheet
Request Information
Size: 50 µl, 200 µl
Isotype: mouse IgG1,k
Clone Name: 1073CT3.1.3
Applications: WB
Datasheet
Request Information
Background:
Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Plays an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics. Required for normal development of peripheral nervous system and skeletal muscle and for muscle satellite cell proliferation. Required for osteoblastogenesis and bone formation. Also prevents fat infiltration of muscle and bone marrow, helping to maintain the volume and strength of skeletal muscle and bone.
Other Names:
Prelamin-A/C, Lamin-A/C, 70 kDa lamin, Renal carcinoma antigen NY-REN-32, LMNA, LMN1
Target/Specificity:
This antibody is generated from a mouse immunized with a recombinant protein.
Antigen Type: Synthesized Peptide
Gene Name: LMNA
Gene ID: 4000
Primary Accession: P02545
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Plays an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics. Required for normal development of peripheral nervous system and skeletal muscle and for muscle satellite cell proliferation. Required for osteoblastogenesis and bone formation. Also prevents fat infiltration of muscle and bone marrow, helping to maintain the volume and strength of skeletal muscle and bone.
Other Names:
Prelamin-A/C, Lamin-A/C, 70 kDa lamin, Renal carcinoma antigen NY-REN-32, LMNA, LMN1
Target/Specificity:
This antibody is generated from a mouse immunized with a recombinant protein.
Antigen Type: Synthesized Peptide
Gene Name: LMNA
Gene ID: 4000
Primary Accession: P02545
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
| Is Featured? | No |
|---|
Write Your Own Review