LMNB2 Polyclonal Antibody

Background:
This gene encodes a B type nuclear lamin. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Mutations in this gene are associated with acquired partial lipodystrophy.

Research Area: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Signal Transduction, Tags and Cell Markers

Synonyms:
LMNB2, EPM9, LAMB2, LMN2, lamin-B2

Immunogen: Recombinant fusion protein of human LMNB2 (NP_116126.3).

Swissprot: Q03252
Gene ID: 84823

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "IHC 1:50-1:200 IF 1:50-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.