LMO3 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS61533
Background:
LMO3 (LIM domain only 3), also known as RBTN3 (Rhombotin-3), RBTNL2 or RHOM3, is a 145 amino acid protein that contains two LIM zinc-binding domains and may be involved in transcriptional regulation events in tissues throughout the body. Aberrant expression of LMO3 is associated with the genesis and progression of human neuroblastoma, suggesting a role for LMO3 in oncogenesis. The gene encoding LMO3 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and Trisomy 12p, which causes facial developmental defects and seizure disorders.
Alternative Name:
LIM domain only protein 3, LMO-3, Neuronal-specific transcription factor DAT1, Rhombotin-3
Application Dilution: WB: 1:500~1:1000
Specificity: LMO3 polyclonal antibody detects endogenous levels of LMO3 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 101-145 of Human LMO3.
MW: ~ 20 kDa
Swis Prot.: Q8TAP4
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 96% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
LMO3 (LIM domain only 3), also known as RBTN3 (Rhombotin-3), RBTNL2 or RHOM3, is a 145 amino acid protein that contains two LIM zinc-binding domains and may be involved in transcriptional regulation events in tissues throughout the body. Aberrant expression of LMO3 is associated with the genesis and progression of human neuroblastoma, suggesting a role for LMO3 in oncogenesis. The gene encoding LMO3 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and Trisomy 12p, which causes facial developmental defects and seizure disorders.
Alternative Name:
LIM domain only protein 3, LMO-3, Neuronal-specific transcription factor DAT1, Rhombotin-3
Application Dilution: WB: 1:500~1:1000
Specificity: LMO3 polyclonal antibody detects endogenous levels of LMO3 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 101-145 of Human LMO3.
MW: ~ 20 kDa
Swis Prot.: Q8TAP4
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 96% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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