LMO7 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS60784
Background:
The LIM-only (LMO) proteins are nuclear factors characterized by a conserved LIM domain. The LIM domain contains a cysteine-rich zinc-binding motif, present in a variety of transcription factors, including the LIM homeobox (LHX) proteins expressed in the central nervous system. The deduced LMO7 protein is comprised of 1,349 amino acid residues, contains a characteristic zinc finger domain and a 3-prime UTR which possesses a short interspersed nucleotide element (SINE). RT-PCR detects predominant expression of LMO7 in heart, lung, skeletal muscle, and kidney, moderate expression in liver, ovary, brain, pancreas, and testis, and little to no expression in spleen. Research indicates that LMO7 is an afadin- and alpha-actinin-binding protein that connects the nectin-afadin and E-cadherin-catenin systems through alpha-actinin.
Alternative Name:
LIM domain only protein 7, LMO-7, F-box only protein 20, LOMP, LMO7, FBX20, FBXO20, KIAA0858
Application Dilution: WB: 1:500~1:1000
Specificity: LMO7 polyclonal antibody detects endogenous levels of LMO7 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human LMO7.
MW: ~ 193 kDa
Swis Prot.: Q8WWI1
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The LIM-only (LMO) proteins are nuclear factors characterized by a conserved LIM domain. The LIM domain contains a cysteine-rich zinc-binding motif, present in a variety of transcription factors, including the LIM homeobox (LHX) proteins expressed in the central nervous system. The deduced LMO7 protein is comprised of 1,349 amino acid residues, contains a characteristic zinc finger domain and a 3-prime UTR which possesses a short interspersed nucleotide element (SINE). RT-PCR detects predominant expression of LMO7 in heart, lung, skeletal muscle, and kidney, moderate expression in liver, ovary, brain, pancreas, and testis, and little to no expression in spleen. Research indicates that LMO7 is an afadin- and alpha-actinin-binding protein that connects the nectin-afadin and E-cadherin-catenin systems through alpha-actinin.
Alternative Name:
LIM domain only protein 7, LMO-7, F-box only protein 20, LOMP, LMO7, FBX20, FBXO20, KIAA0858
Application Dilution: WB: 1:500~1:1000
Specificity: LMO7 polyclonal antibody detects endogenous levels of LMO7 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human LMO7.
MW: ~ 193 kDa
Swis Prot.: Q8WWI1
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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