Lmx1a Antibody (Center) Blocking Peptide
€363.00
In stock
SKU
AC-BP1426c
Background:
Insulin is produced exclusively by the beta cells in the islets of Langerhans in the pancreas. The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear genes that bind to specific sequences within the promoter of the insulin gene (INS; MIM 176730) and interact with RNA polymerase to activate or repress transcription. LMX1 is a homeodomain protein that binds an A/T-rich sequence in the insulin promoter and stimulates transcription of insulin.
Other Names:
LIM homeobox transcription factor 1-alpha, LIM/homeobox protein 11, LMX-11, LIM/homeobox protein LMX1A, Lmx1a
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1426c was selected from the Center region of human Lmx1a. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: Lmx1a
Gene ID: 110648
Primary Accession: Q9JKU8
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Insulin is produced exclusively by the beta cells in the islets of Langerhans in the pancreas. The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear genes that bind to specific sequences within the promoter of the insulin gene (INS; MIM 176730) and interact with RNA polymerase to activate or repress transcription. LMX1 is a homeodomain protein that binds an A/T-rich sequence in the insulin promoter and stimulates transcription of insulin.
Other Names:
LIM homeobox transcription factor 1-alpha, LIM/homeobox protein 11, LMX-11, LIM/homeobox protein LMX1A, Lmx1a
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1426c was selected from the Center region of human Lmx1a. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: Lmx1a
Gene ID: 110648
Primary Accession: Q9JKU8
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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