Lmx1a polyclonal (Center), anti-human, mouse
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In stock
SKU
AC-AP1426c
Catalog Number: AC-AP1426c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB09408
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB09408
Applications: WB
Datasheet
Request Information
Background:
Insulin is produced exclusively by the beta cells in the islets of Langerhans in the pancreas. The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear genes that bind to specific sequences within the promoter of the insulin gene (INS; MIM 176730) and interact with RNA polymerase to activate or repress transcription. LMX1 is a homeodomain protein that binds an A/T-rich sequence in the insulin promoter and stimulates transcription of insulin.
Other Names:
LIM homeobox transcription factor 1-alpha, LIM/homeobox protein 11, LMX-11, LIM/homeobox protein LMX1A, Lmx1a
Target/Specificity:
This Lmx1a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 130-159 amino acids from the Central region of human Lmx1a.
Antigen Region:
130-159
Antigen Type: Synthetic Peptide
Gene Name: Lmx1a
Gene ID: 110648
Primary Accession: Q9JKU8
NCBI Accession: NP_387501.1
Other Accession: Q8TE12
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Insulin is produced exclusively by the beta cells in the islets of Langerhans in the pancreas. The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear genes that bind to specific sequences within the promoter of the insulin gene (INS; MIM 176730) and interact with RNA polymerase to activate or repress transcription. LMX1 is a homeodomain protein that binds an A/T-rich sequence in the insulin promoter and stimulates transcription of insulin.
Other Names:
LIM homeobox transcription factor 1-alpha, LIM/homeobox protein 11, LMX-11, LIM/homeobox protein LMX1A, Lmx1a
Target/Specificity:
This Lmx1a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 130-159 amino acids from the Central region of human Lmx1a.
Antigen Region:
130-159
Antigen Type: Synthetic Peptide
Gene Name: Lmx1a
Gene ID: 110648
Primary Accession: Q9JKU8
NCBI Accession: NP_387501.1
Other Accession: Q8TE12
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
| Is Featured? | No |
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