LONP1 polyclonal, anti-human, mouse, rat

Background:
This gene encodes a mitochondrial matrix protein that belongs to the Lon family of ATP-dependent proteases. This protein mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides in the mitochondrial matrix. It may also have a chaperone function in the assembly of inner membrane protein complexes, and participate in the regulation of mitochondrial gene expression and maintenance of the integrity of the mitochondrial genome. Decreased expression of this gene has been noted in a patient with hereditary spastic paraplegia (PMID:18378094). Alternatively spliced transcript variants have been found for this gene.

Synonyms: CODASS, LON, LONP, LonHS, PIM1, PRSS15, hLON

Cellular Location: Mitochondrion matrix

Immunogen:
Recombinant protein of human LONP1

Gene Symbol: LONP1

Gene ID: 9361

Swiss prot: P36776

Calculated MW: 106kDa

Recommended dilution:
WB 1:500-2000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.