LOX monoclonal (Center), anti-human
€0.00
In stock
SKU
AC-AM2166b
Catalog Number: AC-AM2166b
Size: 80 µl, 400 µl
Isotype: mouse IgG2b
Clone Name: 624CT23.7.3
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: mouse IgG2b
Clone Name: 624CT23.7.3
Applications: WB
Datasheet
Request Information
Background:
The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene.
Other Names:
Protein-lysine 6-oxidase, Lysyl oxidase, LOX
Target/Specificity:
This LOX antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 234-260 amino acids from the Central region of human LOX.
Antigen Region:
234-260
Antigen Type: Synthetic Peptide
Gene Name: LOX
Gene ID: 4015
Primary Accession: P28300
NCBI Accession: NP_002308.2
Other Accession: P16636; P45845; P28301; NP_002308.2
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene.
Other Names:
Protein-lysine 6-oxidase, Lysyl oxidase, LOX
Target/Specificity:
This LOX antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 234-260 amino acids from the Central region of human LOX.
Antigen Region:
234-260
Antigen Type: Synthetic Peptide
Gene Name: LOX
Gene ID: 4015
Primary Accession: P28300
NCBI Accession: NP_002308.2
Other Accession: P16636; P45845; P28301; NP_002308.2
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
| Is Featured? | No |
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