LOX polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS70865
Background:
The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene.
Alternative Name:
Lysyl oxidase, Protein-lysine 6-oxidase
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: LOX polyclonal antibody detects endogenous levels of LOX protein.
Immunogen:
A synthetic peptide of human LOX.
MW: ~ 47 kDa
Swis Prot.: P28300
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene.
Alternative Name:
Lysyl oxidase, Protein-lysine 6-oxidase
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: LOX polyclonal antibody detects endogenous levels of LOX protein.
Immunogen:
A synthetic peptide of human LOX.
MW: ~ 47 kDa
Swis Prot.: P28300
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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