LOX Polyclonal Antibody

Background:
The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene.

Research Area: Cancer, Cardiovascular, Signal Transduction

Synonyms:
lox, LYOX, LYOX, Lysyl oxidase, MGC105112, Protein lysine 6 oxidase, Protein-lysine 6-oxidase

Immunogen: Synthetic peptide of human LOX

Swissprot: P28300
Gene Accession: NP_002308

Calculated MW: 47 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.3 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:25-1:100

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-32409/sc-32410/sc-66947